A Trial of Pembrolizumab in Combination With Chemotherapy and Radiotherapy in Stage III NSCLC (KEYNOTE-799, MK-3475-799). - Full Text View.

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KEYNOTE-799 (ClinicalTrials.gov, NCT03631784) is a Phase 2, non-randomized, open-label study of 216 untreated patients with unresectable, locally advanced stage IIIA–C NSCLC designed to evaluate A trial of pembrolizumab with other treatment for non small cell lung cancer (KEYNOTE-799) Please note - this trial is no longer recruiting patients. We hope to add results when they are available. The phase 2 KEYNOTE-799 study (NCT03631784) enrolled a total of 216 patients with previously untreated, unresectable, pathologically confirmed stage IIIA–C NSCLC, with measurable disease per RECIST 1.1. Cohort A consisted of patients with both squamous and nonsquamous NSCLC, while cohort B included patients with nonsquamous NSCLC only.

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A Trial of Pembrolizumab in Combination With Chemotherapy and Radiotherapy in Stage III NSCLC (KEYNOTE-799, MK-3475-799). - National Cancer Institute A Trial of Pembrolizumab in Combination With Chemotherapy and Radiotherapy in Stage III NSCLC (KEYNOTE-799, MK-3475-799). Status: closed to accrual

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Purpose: In KEYNOTE-189, first-line pembrolizumab plus pemetrexed-platinum significantly improved overall survival (OS) and progression-free survival (PFS) compared with placebo plus pemetrexed-platinum in patients with metastatic nonsquamous non‒small-cell lung cancer (NSCLC), irrespective of tumor programmed death-ligand 1 (PD-L1) expression.

Available  Sep 25, 2018 That study, Keynote-799, will not yield results for a couple of years, so Astra should have this early-stage NSCLC niche to itself for a while  Oct 29, 2020 9-11 In the phase II NICOLAS and KEYNOTE-799 studies, concurrent CRT with nivolumab and pembrolizumab therapy, respectively, have shown  Mar 5, 2021 03 - Pembrolizumab Plus Platinum Chemotherapy and Radiotherapy in Unresectable, Locally Advanced Stage III NSCLC: KEYNOTE-799. Martin Reck, MD, PhD, of the LungenClinic, discusses the results from KEYNOTE -799, which explored a new strategy to increase the intensity of treatment in  NCT03631784, A Trial of Pembrolizumab in Combination With Chemotherapy and Radiotherapy in Stage III NSCLC (KEYNOTE-799, MK-3475-799). WCLC 2020: KEYNOTE-799 Update on Pembrolizumab With Chemoradiotherapy in Stage III Lung Cancer · WCLC 2020: Updated Overall Survival With  2021年2月25日 KEYNOTE-799研究ORR、DoR、1年PFS率和1年OS率. 队列A (n=112)的ORR为 69.6% (95% CI: 60.2-78.0), 4例患者(3.6%)显示完全缓解(CR)  Aug 15, 2018 and Radiotherapy in Stage III NSCLC (KEYNOTE-799, MK-3475-799). Stage III Non-Small Cell Lung Cancer (NSCLC) (KEYNOTE-799). 220 E Chicago Ave Chicago, IL 60611. Directions · Contact Form; General: 312- 280-2660; Box Office: 312-397-4010; Store: 312-397-4000; Marisol: 312-799-  Dec 28, 2020 KEYNOTE-799 is a non-randomized, open-label phase II study evaluating pembrolizumab (200 mg IV every 3 weeks) concomitant with chemo-.

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